| Company Name: |
Wuhan chuang he chemical co. LTD
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| Tel: |
15907120073 |
| Email: |
1261789306@qq.com |
| Products Intro: |
Product Name:KI696 isomer
CAS:1799974-69-8
Purity:98 Package:1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:KI696 isomer
CAS:1799974-69-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | KI696 isomer Basic information |
| Product Name: | KI696 isomer | | Synonyms: | KI696 isomer;1H-Benzotriazole-5-propanoic acid, β-[3-[[(4R)-3,4-dihydro-4-methyl-1,1-dioxido-2H-5,1,2-benzoxathiazepin-2-yl]methyl]-4-methylphenyl]-7-methoxy-1-methyl-, (βR)- | | CAS: | 1799974-69-8 | | MF: | C28H30N4O6S | | MW: | 550.63 | | EINECS: | | | Product Categories: | | | Mol File: | 1799974-69-8.mol |  |
| | KI696 isomer Chemical Properties |
| Boiling point | 760.5±70.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 125 mg/mL (227.01 mM);Water : < 0.1 mg/mL (insoluble) | | pka | 4.28±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | KI696 isomer Usage And Synthesis |
| Description | KI696 isomer is the less active isomer of KI696. KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction.
| | References | [1]. Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59(8):3991-4006. |
| | KI696 isomer Preparation Products And Raw materials |
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