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Shanghai Haohong Pharmaceutical Co., Ltd. Gold
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Product Name:3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
CAS:952143-02-1
Purity:98% Package:1g
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ChemShuttle, Inc.
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0510-83588313-802 18800520310; |
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Product Name:3-(4-bromophenyl)-3-(trifluoromethyl)-3H-diazirine
CAS:952143-02-1
Purity:95% Package:5mg;25mg;100mg;500mg;1g;5g;10g;25g;50g;100g;250g;500g;kg…
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Sigma-Aldrich
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orderCN@merckgroup.com |
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Product Name:3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
CAS:952143-02-1
Purity:3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine Package:50MG Remarks:906298-50MG
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| Company Name: |
Taizhou GreenChem Pharmaceutical Co., Ltd.
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0514-86654616 15366892466 |
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greenchem@tzglmk.com |
| Products Intro: |
Product Name:3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
CAS:952143-02-1
Purity:95% Package:1g;10g;100g;
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| | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine Basic information |
| | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine Chemical Properties |
| Boiling point | 228.5±50.0 °C(Predicted) | | density | 1.81±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C |
| | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine Usage And Synthesis |
| Uses | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine is a Suzuki-Miyaura (S?M)-compatible building block tailored for the design of photoaffinity probes (PAPs). Photoaffinity labeling (PAL) is of growing interest in chemical biology and drug discovery research for use in protein profiling; covalent inhibitors; protein-protein interactions and complexes; and target engagement, identification, or validation studies. Diazirines are desirable photoactivable groups for chemical probes; however, their installation is not always straightforward. In response, diazirine-tolerant S-M coupling conditions were developed by Ichiishi, et al, using 3-(4-bromophenyl)-3-(trifluoromethyl)-3H-diazirine and shown to be efficient and scalable with minimal perturbation of the diazirine. |
| | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine Preparation Products And Raw materials |
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