Company Name: |
Bejing Famous Pharmaceutical Technology Co., Ltd.
|
Tel: |
13331045123 |
Email: |
1963319514@qq.com |
Products Intro: |
Product Name:(S)-IDO1-IN-5 CAS:2166616-76-6 Purity:97% Package:1g/;5g/;10g/;25g/;50g/;100g/;250g/;500g/;1kg/;5kg/;10kg/;25kg/;50kg/;100kg/;250kg/;500kg/
|
Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:(S)-IDO1-IN-5 CAS:2166616-76-6 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
|
| (S)-IDO1-IN-5 Basic information |
Product Name: | (S)-IDO1-IN-5 | Synonyms: | (S)-IDO1-IN-5;(S)IDO1IN5,(S)-IDO-1-IN-5,(S) IDO1 IN 5;Benzamide, N-[(1S)-1-[2,3-dihydro-1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-1H-indol-5-yl]ethyl]-4-fluoro- | CAS: | 2166616-76-6 | MF: | C23H25FN2O3 | MW: | 396.45 | EINECS: | | Product Categories: | | Mol File: | 2166616-76-6.mol | |
| (S)-IDO1-IN-5 Chemical Properties |
Boiling point | 665.5±55.0 °C(Predicted) | density | 1.251±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO: 300 mg/mL (756.72 mM) | pka | 13.93±0.46(Predicted) | form | Solid | color | White to off-white |
| (S)-IDO1-IN-5 Usage And Synthesis |
Description | (S)-IDO1-IN-5 is the S-isomer of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1]. | References | [1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13). |
| (S)-IDO1-IN-5 Preparation Products And Raw materials |
|