A-7 HYDROCHLORIDE

A-7 HYDROCHLORIDE Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:A-7 hydrochloride
CAS:79127-24-5
Package:10 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:N-(10-AMinodecyl)-5-chloro-1-naphthalenesulfonaMide Hydrochloride
CAS:79127-24-5
Package:250Mg,25Mg
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:A-7 hydrochloride;N-(10-AMinodecyl)-5-chloro-1-naphthalenesulfonaMidehydrochloride
CAS:79127-24-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: Chemsky(shanghai)International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:N-(10-AMinodecyl)-5-chloro-1-naphthalenesulfonaMide Hydrochloride
CAS:79127-24-5
Purity:98%
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Products Intro: Product Name:A-7 hydrochloride
CAS:79127-24-5
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
A-7 HYDROCHLORIDE Basic information
Product Name:A-7 HYDROCHLORIDE
Synonyms:N-(10-AMINODECYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;A-7 HYDROCHLORIDE;N-(10-Aminodec-1-yl)-5-chloronaphthalene-1-sulphonamide hydrochloride;1-[(10-Aminodec-1-yl)sulphamoyl]-5-chloronaphthalene;N-(10-AMinodecyl)-5-chloro-1-naphthalenesulfonaMide Monoydrochloride;N-(10-Aminodec-1-yl)-5-chloronaphthalene-1-sulfonamide hydrochloride;A7 hydrochloride,A 7 hydrochloride
CAS:79127-24-5
MF:C20H29Cl2NO2S
MW:418.42
EINECS:
Product Categories:Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Calcium signaling;Protein Kinase Inhibitors and Activators
Mol File:Mol File
A-7 HYDROCHLORIDE Structure
A-7 HYDROCHLORIDE Chemical Properties
Melting point 186-188°C
storage temp. Store at RT
solubility Soluble to 50mM in DMSO
form White to off-white crystalline powder.
color Pale Yellow to Yellow
CAS DataBase Reference79127-24-5
Safety Information
HS Code 2935909099
MSDS Information
A-7 HYDROCHLORIDE Usage And Synthesis
Chemical PropertiesWhite Crystalline Solid
UsesCalmodulin antagonist
UsesCalmodulin is a calcium-dependent protein that regulates the activity of a diverse array of enzymes, ion channels, and other proteins and thus has diverse roles in cell function. A-7 is an analog of the napthalenesulfonamide W-7 that has an acyl chain length of 10 carbons, rather than six. It is a potent cell-permeable antagonist of calmodulin that inhibits Ca2+/calmodulin cyclic nucleotide phosphodiesterase more potently than W-7 (IC50 = 3.2 and 26 μM, respectively).
UsesNaphthalenesulfonamides
Biological ActivityPotent calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC 50 of 3 μ M).
storageRoom temperature
A-7 HYDROCHLORIDE Preparation Products And Raw materials
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