TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 )
生物活性靶点体外研究体内研究 用途与合成方法 MSDS TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 )价格(试剂级) 上下游产品信息
| 中文名称 | TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 ) |
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| 中文同义词 | |
| 英文名称 | ADRENOMEDULLIN 1-50, RAT |
| 英文同义词 | YRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGY-NH2 (DISULFIDE BRIDGE: 14-19);ADRENOMEDULLIN 1-50, RAT;H-TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE: 14-19);Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-;TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 );TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2: YRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGY;L-Arginine, L-tyrosyl-L-arginyl-L-glutaminyl-L-seryl-L-methionyl-L-asparaginyl-L-asparaginyl-L-phenylalanyl-L-alanylglycyl-L-leucyl- (9CI);Adrenomedullin rat >=95% (HPLC) |
| CAS号 | 159964-38-2 |
| 分子式 | C62H97N21O18S |
| 分子量 | 1456.63 |
| EINECS号 | |
| 相关类别 | 多肽;peptide;AdrenomedullinPeptides for Cell Biology;Adrenomedullins;Hormones;Miscellaneous Peptides;Other Protein/Peptide Hormones |
| Mol文件 | 159964-38-2.mol |
| 结构式 |  |
TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 ) 性质
| 密度 | 1.51±0.1 g/cm3(Predicted) |
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| 储存条件 | -20°C |
| 酸度系数(pKa) | 3.34±0.10(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 ) 用途与合成方法
Adrenomedullin (1-50), rat 是由 50 个氨基酸组成的多肽，能够通过激活 CGRP1 受体来诱导动脉血管舒张。
CGRP1 receptor
Adrenomedullin (1-50), rat is a 50 amino acid peptide, which induces a selective arterial vasodilation via activation of CGRP1 receptor.
Adrenomedullin (1-50), rat causes a dose-dependent and endothelium-independent vasodilation on the arterial mesenteric vasculature, and this effect is inhibited by CGRP1 receptor antagonist. Adrenomedullin (1-50), rat activates CGRP1 receptor in the double-perfused mesenteric bed of the rat. Adrenomedullin (1-50) ameliorates pulmonary vascular structural remodeling of hypoxic rats with incresed plasma NO and H(2)S concentrations. Adrenomedullin (1-50) also regulates the development of hypoxic pulmonary hypertension and hypoxic pulmonary vascular structural remodeling, through promoting NO and H(2)S production in hypoxic rats.
安全信息
| WGK Germany | 3 |
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/08/19 | HY-P1534 | TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 ) Adrenomedullin (1-50), rat | 159964-38-2 | 500μg | 2500元 |
| 2024/08/19 | HY-P1534 | TYR-ARG-GLN-SER-MET-ASN-GLN-GLY-SER-ARG-SER-THR-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-MET-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-GLY-MET-ALA-PRO-ARG-ASN-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE:CYS14-CYS19 ) Adrenomedullin (1-50), rat | 159964-38-2 | 1mg | 3500元 |