ANTI-H2AX (PSER139) RABBIT PAB

ANTI-H2AX (PSER139) RABBIT PAB Suppliers list

Company Name:	Sigma-Aldrich
Tel:	021-61415566 800-8193336
Email:	orderCN@merckgroup.com
Products Intro:	Product Name:Anti-phospho-Histone H2AX (pSer139) Purity:IgG fraction of antiserum, buffered aqueous solution Package:200μL Remarks:H5912

Company Name:	Riedel-de Haen AG
Tel:	800 558-9160
Email:
Products Intro:	Product Name:Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit Remarks:IgG fraction of antiserum, buffered aqueous solution

ANTI-H2AX (PSER139) RABBIT PAB Basic information

Product Name:	ANTI-H2AX (PSER139) RABBIT PAB
Synonyms:	ANTI-PHOSPHO-HISTONE H2AX [PSER139];ANTI-H2AX (PSER139) RABBIT PAB;Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit;Anti-H2AXS139p
CAS:
MF:
MW:	0
EINECS:
Product Categories:	Alphabetical Index;Antibodies for EpigeneticsAntibodies for Gene Regulation and Expression;Antibodies for Gene Regulation and Expression;Antibodies in Chromatin Remodeling;Antibodies to Histone ModificationsCell Biology;Antibodies to Transcription RegulatorsAntibodies;Functional Profiling of Stem Cells;H;Stem Cell Biology
Mol File:	Mol File

ANTI-H2AX (PSER139) RABBIT PAB Chemical Properties

storage temp.	−20°C
form	buffered aqueous solution

Safety Information

Safety Statements	23-24/25
WGK Germany	2

MSDS Information

Provider	Language
SigmaAldrich	English

ANTI-H2AX (PSER139) RABBIT PAB Usage And Synthesis

Uses	Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit has been used in immunofluorescence and western blotting.
General Description	H2AX comprises 2-25% of the total H2A complement in human cells, whereas in the budding yeast it constitutes virtually all of the H2A molecules. It has N-terminal and C-terminal region with a central globular domain. The C-terminal region has sites for modification including acetylation, biotinylation and phosphorylation.
Biochem/physiol Actions	H2AX is critical for facilitating the assembly of specific DNA-repair complexes on damaged DNA. Ataxia-telangiectasia-mutated (ATM) is the major kinase involved in the phosphorylation of H2AX in response to DNA double-strand breaks. H2AX knockout mice are radiation sensitive and show retarted growth. They also are immune deficient with mutant males are infertile..

ANTI-H2AX (PSER139) RABBIT PAB Preparation Products And Raw materials

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