Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:N-(p-Amylcinnamoyl)anthranilic acid CAS:99196-74-4 Purity:>=98% (HPLC) Package:5mg, 25mg Remarks:A8486
|
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Email: |
marketing@energy-chemical.com |
Products Intro: |
Product Name:N-(p-Amylcinnamoyl)anthranilic acid >=98% (HPLC) CAS:99196-74-4 Purity:98% (HPLC) Package:25mg;5mg Remarks:NULL
|
|
Product Name: | ACA | Synonyms: | AMARANTHUS CAUDATUS LECTIN;ACA;ACL;2-[[1-oxo-3-(4-Pentylphenyl)-2-propen-1-yl]amino]-benzoic acid;N-(4-Pentylcinnamoyl)anthranilic acid;GAMRBCZMOOMBSQ-CCEZHUSRSA-N;2-[3-(4-pentylphenyl)prop-2-enoylamino]benzoic acid;N-(p-Amylcinnamoyl)anthranilic acid >=98% (HPLC) | CAS: | 99196-74-4 | MF: | C21H23NO3 | MW: | 337.41 | EINECS: | | Product Categories: | | Mol File: | 99196-74-4.mol | |
Boiling point | 563.1±50.0 °C(Predicted) | density | 1.178±0.06 g/cm3(Predicted) | storage temp. | room temp | solubility | DMSO: ≥20mg/mL | form | powder | pka | 3.46±0.36(Predicted) | color | white to off-white |
Hazard Codes | N | Risk Statements | 50/53 | Safety Statements | 60-61 | RIDADR | UN 3077 9 / PGIII | WGK Germany | 3 |
Uses | N-(p-Amylcinnamoyl)anthranilic acid has been used as a transient receptor potential cation channel subfamily M member 2 (TRPM2) inhibitor, in studying its role in regulating the production of reactive oxygen species (ROS). | Definition | ChEBI: N-(p-amylcinnamoyl)anthranilic acid is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor. It has a role as an EC 3.1.1.4 (phospholipase A2) inhibitor and a TRP channel blocker. It is an amidobenzoic acid, a member of cinnamamides and a secondary carboxamide. | General Description | N-(p-Amylcinnamoyl)anthranilic acid (ACA) functions as a broad spectrum phospholipase A2 inhibitor and blocks transient receptor potential (TRP) channels. It inhibits calcium activated chloride current in cardiac ventricular myocytes. ACA regulates various ion channels. | Biochem/physiol Actions | Broad spectrum phospholipase A2 (PLA2) inhibitor and TRP channel blocker. |
| ACA Preparation Products And Raw materials |
|