脱乙基氯喹二磷酸盐
中文名称 | 脱乙基氯喹二磷酸盐 |
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中文同义词 | 脱乙基氯喹二磷酸盐;化合物 T11001L;13C6]-去乙基氯喹二磷酸盐 |
英文名称 | Desethylchloroquine diphosphate salt |
英文同义词 | Desethylchloroquine diphosphate salt;Desethyl chloroquine diphosphate |
CAS号 | 247912-76-1 |
分子式 | C16H25ClN3O4P |
分子量 | 389.82 |
EINECS号 | |
相关类别 | |
Mol文件 | 247912-76-1.mol |
结构式 | ![]() |
脱乙基氯喹二磷酸盐 性质
储存条件 | 4°C, protect from light, stored under nitrogen |
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溶解度 | 溶于二甲基亚砜 |
形态 | 固体 |
颜色 | 白色至米白色 |
P. falciparum
Intraperitoneal injections of Chloroquine are administered to wild-type and Huntington's disease (Q175/Q175) mice. LC-MS/MS is used to compare the levels Chloroquine and its metabolites in blood, brain and muscle tissue. Concentrations of Chloroquine are lower (5-15M), but more stable in brain tissue compared to blood or muscle between 4 and 24 hours after the last dose. Levels of the active Chloroquine metabolite Desethyl chloroquine decreased in muscle and blood over the 24 hour post-injection period, while brain Desethyl chloroquine levels are lower and rose slightly over the same time frame.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/04/30 | HY-135811A | Desethyl chloroquine diphosphate | 1 mg | 1818元 | |
2024/04/30 | HY-135811A | 脱乙基氯喹二磷酸盐 Desethyl chloroquine diphosphate | 247912-76-1 | 5mg | 4000元 |