Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- manufacturers
- BC-1471
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- $56.00 / 1mg
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2024-11-19
- CAS:896683-84-4
- Min. Order:
- Purity: 99.18%
- Supply Ability: 10g
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| Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Basic information |
Product Name: | Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- | Synonyms: | Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]-;IL-1β,Inhibitor,STAM-binding protein,inhibit,BC-1471,BC1471,DUBs,STAMBP,NALP7,BC 1471,Deubiquitinase | CAS: | 896683-84-4 | MF: | C27H32N4O4S | MW: | 508.63 | EINECS: | | Product Categories: | | Mol File: | 896683-84-4.mol | |
| Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Chemical Properties |
storage temp. | Store at -20°C | solubility | DMSO : 50 mg/mL (98.30 mM; Need ultrasonic) | form | Solid | color | White to off-white |
| Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Usage And Synthesis |
Definition | ChEBI: 2-[[6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-(2-oxolanylmethyl)acetamide is a member of quinazolines. | Biological Activity | BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits NALP7 (NACHT, LRR and PYD domains-containing protein 7) inflammasome activity[1]. | References | [1]. Bednash JS, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017 May 11;8:15203. |
| Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-[(tetrahydro-2-furanyl)methyl]- Preparation Products And Raw materials |
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