Sign in | Register | china | japan | germany

1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl-

Request For Quotation
1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:SR-318
CAS:2413286-32-3
Purity:99.53% Package:5mg;53USD|10mg;88USD|25mg;178USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:SR-318
CAS:2413286-32-3
Purity:99.53% Package:5mg;53USD|10mg;88USD|25mg;178USD
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Products Intro: Product Name:SR-318
CAS:2413286-32-3
Purity:99% Package:1mg;2mg;5mg
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:SR-318
CAS:2413286-32-3
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: ShangHai ChuanQian Chemcial Technique Centre  
Tel: 15869524721
Email: 3525679403@qq.com
Products Intro: Product Name:SR-318
CAS:2413286-32-3
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G,10G

1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- manufacturers

  • SR-318
  • SR-318 pictures
  • $53.00 / 5mg
  • 2024-11-19
  • CAS:2413286-32-3
  • Min. Order:
  • Purity: 99.53%
  • Supply Ability: 10g
  • SR-318
  • SR-318 pictures
  • $53.00 / 5mg
  • 2024-11-19
  • CAS:2413286-32-3
  • Min. Order:
  • Purity: 99.53%
  • Supply Ability: 10g
1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- Basic information
Product Name:1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl-
Synonyms:1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl-;SR-318;anti-inflammatory,SR 318,TNFR,anti-cancer,p38 MAPK,Inhibitor,inhibit,whole,TNF Receptor,SR-318,SR318,p38α/β,Tumor Necrosis Factor Receptor,blood;SR-318, 10 mM in DMSO
CAS:2413286-32-3
MF:C27H33N5O2
MW:459.58
EINECS:
Product Categories:
Mol File:2413286-32-3.mol
1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- Structure
1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- Chemical Properties
Boiling point 732.0±60.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO:40.0(Max Conc. mg/mL);87.03(Max Conc. mM)
form A solid
pka13.10±0.46(Predicted)
color White to off-white
Safety Information
MSDS Information
1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- Usage And Synthesis
Biological ActivitySR-318 is a potent and selective type-II inhibitor th at targets p38α/β in an inactive DFG-out conformation with good kinome selectivity (p38α/β IC50 = 5/39 nM by radiometric kinase assay). SR-318 selectively inhibits p38α/β by cell-based NanoBRET assay (IC50 = 3.7 nM/p38α, 10 nM/p38β, 0.91 μM/ZAK, ≥3 μM/DDR1, DDR2, KIT, MYLK4, RSK4) and effectively blocks LPS-induced TNF-α release in human whole blood (IC50 = 283 nM). SR-321 is an inactive structural analog and the recommended negative control compound.
1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl- Preparation Products And Raw materials
Tag:1H-Pyrazole-4-carboxamide, 5-amino-N-[[4-[[(3-cyclohexylpropyl)amino]carbonyl]phenyl]methyl]-1-phenyl-(2413286-32-3) Related Product Information