| Company Name: |
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
|
| Tel: |
025-86755008 17751752005 |
| Email: |
hszhang@bestfluorodrug.com |
| Products Intro: |
Product Name:1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
CAS:2412056-48-3
Purity:95%+ Package:1g;5g;10g,25g
|
| Company Name: |
Shanghai Easy CDMO Co.,Ltd
|
| Tel: |
021-61734564 |
| Email: |
August@easycdmo.com |
| Products Intro: |
Product Name:INDEX NAME NOT YET ASSIGNED
CAS:2412056-48-3
Purity:98% Package:5g；10g；20g；100g；100kg
|
| Company Name: |
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
|
| Tel: |
025-86755008 17751752005 |
| Email: |
hszhang@bestfluorodrug.com |
| Products Intro: |
Product Name:1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
CAS:2412056-48-3
Purity:95%+ Package:1g;5g;10g;25g
|
|
| | INDEX NAME NOT YET ASSIGNED Basic information |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| Boiling point | 773.6±60.0 °C(Predicted) | | density | 1.385±0.06 g/cm3(Predicted) | | solubility | DMSO : 80 mg/mL (153.40 mM; Need ultrasonic) | | pka | 4.28±0.10(Predicted) | | form | Solid-Liquid Mixture | | color | Yellow to green |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Biological Activity | Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].
Thalidomide-NH-PEG4-COOH (S13) is the E3 ligase ligand-linker conjugate of dCBP-1[1]. | | References | [1]. Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4. |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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