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Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-

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Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)- Suppliers list
Company Name: Shanghai Guangyang Jiali Biotechnology Co., Ltd
Tel: 13407521611
Email: 46993711@qq.com
Products Intro: CAS:2166375-82-0
Package:2
Company Name: Shanghai Guangyang Carrie Biotechnology Co., LTD  
Tel: 18616826356
Email: 1942593824@qq.com
Products Intro: CAS:2166375-82-0
Package:1g;5g
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:Glucocorticoid receptor agonist-1
CAS:2166375-82-0
Purity:99.51% Package:100 mg；50 mg；1 mg；5 mg；10 mg；25 mg；；
Company Name: Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.  
Tel: 025-66061636 18013972705
Email: qqyang@aikonchem.com
Products Intro: CAS:2166375-82-0
Purity:95% Package:1g;5g;10g
Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)- Basic information
Product Name:Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-
Synonyms:Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-;Glucocorticoid receptor agonist-1;Glucocorticoid receptor agonist 1,Glucocorticoid receptor agonist1
CAS:2166375-82-0
MF:C35H39NO6
MW:569.7
EINECS:
Product Categories:
Mol File:2166375-82-0.mol
Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)- Structure
Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)- Chemical Properties
Boiling point 778.5±60.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
storage temp. 4°C, protect from light
form Solid
pka12.87±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)- Usage And Synthesis
Biological ActivityGlucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41[1]. Glucocorticoid receptor agonist immunoconjugates are useful for treating autoimmune diseases such as, but not limited to, rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult Crohn’s disease, pediatric Crohn’s disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, uveitis, Behcets disease, a spondyloarthropathy, or psoriasis[1].
References[1]. Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.
Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)- Preparation Products And Raw materials
Tag:Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-(2166375-82-0) Related Product Information