| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:DS44960156
CAS:2361327-08-2
Purity:98% HPLC Package:100mg，250mg，1g
|
|
| | Benzoic acid, 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]- Basic information |
| | Benzoic acid, 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]- Chemical Properties |
| Boiling point | 652.9±55.0 °C(Predicted) | | density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: soluble,Methanol: soluble | | form | A crystalline solid | | pka | 3.86±0.10(Predicted) | | color | White to off-white |
| | Benzoic acid, 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]- Usage And Synthesis |
| Biological Activity | DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2; IC50 = 1.6 μM).1 It is selective for MTHFD2 over MTHFD1 (IC50 = >30 μM). | | References | 1.Kawai, J., Ota, M., Ohki, H., et al.Structure-based design and synthesis of an isozyme-selective MTHFD2 inhibitor with a tricyclic coumarin scaffoldACS Med. Chem. Lett.10(6)893-898(2019) |
| | Benzoic acid, 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]- Preparation Products And Raw materials |
|