| 中文名称 | Urotensin II,mouse TFA |
|---|---|
| 中文同义词 | |
| 英文名称 | Urotensin II,mouse TFA |
| 英文同义词 | Urotensin II,mouse TFA |
| CAS号 | |
| 分子式 | |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | Mol File |
| 结构式 |
Urotensin II,mouse TFA 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 白色至米白色 |
Urotensin II, mouse TFA 是孤儿 G 蛋白偶联受体 GPR14 或 SENR 的一种内源性配体。Urotensin II, mouse TFA 是一种有效的血管收缩剂。在中枢神经系统中起着重要作用。
GPR14
Urotensin II is a somatostatin-like cyclic peptide which functions as an arterial vasocontrictor, vasodilator, and bronchoconstriction mediator.
Urotensin II (0.1 nmol, 0.3 nmol, and 3 nmol; intracerebroventricular administration) induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner.
| Animal Model: | Male C57BL/6N mice (8 weeks old) |
| Dosage: | 0.1 nmol, 0.3 nmol, and 3 nmol |
| Administration: | Intracerebroventricular (i.c.v.) administration |
| Result: | Decreased the amount of head dipping without significant alteration of the motor activity. |