| Company Name: |
MQ (shanghai) Pharmaceuticals Co., Ltd.
|
| Tel: |
13761635123 |
| Email: |
1014988033@qq.com |
| Products Intro: |
Product Name:methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride
CAS:7210-92-6
|
| Company Name: |
Shaanxi Dideu Newmaterial Co., Ltd.
|
| Tel: |
029-87576359 15353716720 |
| Email: |
1039@dideu.com |
| Products Intro: |
Product Name:methyl 2-[[2-(diethylamino)acetyl]amino]-3-methylbenzoate,hydrochloride
CAS:7210-92-6
Purity:98% Package:25kg
|
| Company Name: |
CLEARSYNTH LABS LTD.
|
| Tel: |
+91-22-45045900 |
| Email: |
sales@clearsynth.com |
| Products Intro: |
Product Name:Tolycaine Hydrochloride
CAS:7210-92-6
|
| Company Name: |
United States Biological
|
| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:Tolycaine Hydrochloride
CAS:7210-92-6
|
|
| | methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Basic information |
| Product Name: | methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride | | Synonyms: | methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride;Baycaine;Tolycaine hydrochloride;LIWOWASNSWUKPF-UHFFFAOYSA-N;methyl 2-[[2-(diethylamino)acetyl]amino]-3-methylbenzoate,hydrochloride;Benzoic acid,2-[[2-(diethylamino)acetyl]amino]-3-methyl-, methyl ester, hydrochloride (1:1) | | CAS: | 7210-92-6 | | MF: | C15H23ClN2O3 | | MW: | 314.80772 | | EINECS: | 2305907 | | Product Categories: | | | Mol File: | 7210-92-6.mol | ![methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Structure](CAS/GIF/7210-92-6.gif) |
| | methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Chemical Properties |
| Melting point | 139-140.5° | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White |
| | methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Usage And Synthesis |
| Originator | Tolycaine
Hydrochloride,ZYF Pharm Chemical | | Uses | Tolycaine Hydrochloride is an anesthetic drug. | | Definition | ChEBI: Tolycaine hydrochloride is an amidobenzoic acid. | | Manufacturing Process | A suspension of 40 g 2-amino-3-methylbenzoic acid methyl ester in 125 ml of
benzene was added 125 ml of saturated solution of sodium acetate and then
at 0-5°C was added 37 g chloracetylchloride. The mixture was stirred for 1
hour at room temperature. The mixture was filtered. The organic layer was
with 10% solution of potassium carbonate and dries under calcium chloride.
By distillation of the mixture was obtained 15 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl ester; melting point 86-87.5°C (crystallization from
a mixture acetic acid and ligroin); yield 21.8 g.
A mixture of 16 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl
ester and 10 g diethyl amine in benzene was refluxed for 5 hours. After
cooling the diethyl amine hydrochloride was deleted by filtration. The organic
layer was washed with 2 N hydrochloric acid. To the solution was added
potassium carbonate. The product was extracted with ether and distilled. | | Therapeutic Function | Local anesthetic |
| | methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Preparation Products And Raw materials |
|