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Product Name:Armeniaspirol A
CAS:1206881-47-1
Remarks:Armeniaspirol A is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that
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| | Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- Basic information |
| Product Name: | Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- | | Synonyms: | Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)-;Armeniaspirol A | | CAS: | 1206881-47-1 | | MF: | C18H19Cl2NO4 | | MW: | 384.25 | | EINECS: | | | Product Categories: | | | Mol File: | 1206881-47-1.mol | ![Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- Structure](CAS/20211123/GIF/1206881-47-1.gif) |
| | Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- Chemical Properties |
| Boiling point | 608.8±55.0 °C(Predicted) | | density | 1.43±0.1 g/cm3(Predicted) | | pka | 7.51±0.60(Predicted) |
| | Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- Usage And Synthesis |
| Description | Armeniaspirols, a novel class of natural products isolated from Streptomyces armeniacus, have been previously identified as antibacterial agents against Gram-positive pathogens. Studies found that armeniaspirol A (ARM1) exhibited potent antibacterial activity against H. pylori, including multidrug-resistant strains, with MIC range values of 4-16 μg ml-1 . The underlying mechanism of action of ARM1 against H. pylori involved the disruption of bacterial cell membranes. |
| | Spiro[benzofuran-2(3H),2'-[2H]pyrrole]-3,5'(1'H)-dione, 3',4'-dichloro-7-hexyl-6-hydroxy-1'-methyl-, (2R)- Preparation Products And Raw materials |
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