|
| 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]- Basic information |
| 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]- Chemical Properties |
Boiling point | 612.0±65.0 °C(Predicted) | density | 1.198±0.06 g/cm3(Predicted) | pka | 12.86±0.40(Predicted) |
| 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]- Usage And Synthesis |
Description | OAT-2068 is a potent, selective, and orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1). OAT-2068 displays a remarkable 143-fold mCHIT1 vs. mAMCase selectivity. OAT-2068 was found to have an excellent pharmacokinetic profile. OAT-2068 represents a highly potent and the most selective inhibitor of mCHIT1 described to date. |
| 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]- Preparation Products And Raw materials |
|