| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Covidcil-19
CAS:1225177-95-6
Purity:详情请点击官网 Package:1 mg
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| | Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Basic information |
| | Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Chemical Properties |
| Boiling point | 580.2±60.0 °C(Predicted) | | density | 1.414±0.06 g/cm3(Predicted) | | solubility | To be determined:2.94(Max Conc. mg/mL);10.0(Max Conc. mM) | | pka | 3.88±0.10(Predicted) |
| | Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Usage And Synthesis |
| Description | Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by > 3.5 orders of magnitude. | | Uses | 3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic Acid is used in the preparation of some molecular binders that targets the SARS-CoV-2 RNA genome, the causative agent of COVID-??19. | | storage | Store at -20°C |
| | Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Preparation Products And Raw materials |
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