Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:Cyclic-di-GMP diammonium CAS:609343-82-0 Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
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3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) manufacturers
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| 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) Basic information |
| 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) Chemical Properties |
storage temp. | Store at -20°C | form | Solid | color | White to off-white |
| 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) Usage And Synthesis |
Biological Activity | Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species[1][2]. | References | [1]. Wang Z, et al. STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice. Cancer Immunol Immunother. 2015;64(8):1057-1066. [2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8. |
| 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) Preparation Products And Raw materials |
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