| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:(±)-MMT5-14
CAS:2719679-31-7
Purity:98% Package:500μg;1mg;5mg
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:MMT5-14
CAS:2719679-31-7
Purity:详情请点击官网 Package:1 mg
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:(±)-MMT5-14
CAS:2719679-31-7
|
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| | INDEX NAME NOT YET ASSIGNED Basic information |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: 20 mg/mL,DMSO: 16 mg/mL,Ethanol: 16 mg/mL | | form | A solid | | pka | 12.00±0.70(Predicted) |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Biological Activity | (±)-MMT5-14 is a derivative of remdesivir with antiviral activity.1 It increases the viability of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50 = 0.4 μM), as well as Vero E6 cells infected with the Alpha, Beta, Gamma, or Delta SARS-CoV-2 variants (EC50s = 2.5, 15.9, 1.7, and 5.6 μM, respectively). (±)-MMT5-14 exhibits increased plasma and lung concentrations compared with remdesivir in hamsters when administered at a dose of 10 mg/kg. | | References | 1.Hu, H., Traore, M.D.M., Li, R., et al.Optimization of the prodrug moiety of remdesivir to improve lung exposure/selectivity and enhance anti-SARS-CoV-2 activityJ. Med. Chem.65(18)12044-12054(2022) |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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