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4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide

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Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: CAS:154540-49-5
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name:Fluoroclebopride
CAS:154540-49-5
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
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Products Intro: Product Name:fluoroclebopride
CAS:154540-49-5
Purity:99% Package:5KG;1KG Remarks:fluoroclebopride
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Products Intro: Product Name:Fluoroclebopride
CAS:154540-49-5
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Products Intro: Product Name:Fluoroclebopride
CAS:154540-49-5
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4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Basic information
Product Name:4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide
Synonyms:4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide;fluoroclebopride;Benzamide,4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-;Inhibitor,inhibit,Fluoroclebopride,Dopamine Receptor
CAS:154540-49-5
MF:C20H23ClFN3O2
MW:391.87
EINECS:
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Mol File:154540-49-5.mol
4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Structure
4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Chemical Properties
Boiling point 518.2±50.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka13.62±0.20(Predicted)
color White to off-white
Safety Information
MSDS Information
4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Usage And Synthesis
DescriptionFluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications. It binds reversibly to dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2-like, D2(long), D3, and D4 receptors, respectively, in radioligand binding assays). It is selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively). A fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models.
4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Preparation Products And Raw materials
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