D2343
中文名称 | D2343 |
---|---|
中文同义词 | 化合物 T15042 |
英文名称 | D 2343 |
英文同义词 | D 2343;2-[[3-(2-Methoxyphenyl)-1,1-dimethylpropyl]amino]-1-(p-hydroxyphenyl)ethanol;Benzenemethanol, 4-hydroxy-α-[[[3-(2-methoxyphenyl)-1,1-dimethylpropyl]amino]methyl]-;D-2343,D2343 |
CAS号 | 72734-63-5 |
分子式 | C20H27NO3 |
分子量 | 329.43 |
EINECS号 | |
相关类别 | |
Mol文件 | 72734-63-5.mol |
结构式 |
D2343 性质
储存条件 | Store at -20°C |
---|---|
溶解度 | 溶于二甲基亚砜 |
β2-adrenoceptor
α1- adrenoceptor
D2343 is a compound with about the same beta 2-adrenoceptor-agonist effect as Terbutaline and exhibiting in addition an alpha 1-receptor inhibitory activity. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM.
D2343 has been compared to the beta 2-agonist Terbutaline on oestrogenized uterine preparations from rat and rabbit and in myometrial strips from homo. D2343 has shown an ability to relax the uterine muscles to the same degree as Terbutaline or even more, especially when the two drugs are compared in preparations from rabbit and rat.