| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:FD-211
CAS:162341-24-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:FD-211
CAS:162341-24-4
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| Product Name: | FD 211 | | Synonyms: | FD 211;5H-Furo[3,4-b]pyran-5-one, 2,3,7,7a-tetrahydro-3-hydroxy-2,7-di-(1E)-1-propen-1-yl-, (2R,3R,7S,7aR)- | | CAS: | 162341-24-4 | | MF: | C13H16O4 | | MW: | 236.26 | | EINECS: | | | Product Categories: | | | Mol File: | 162341-24-4.mol |  |
| | FD 211 Chemical Properties |
| Boiling point | 442.3±45.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Dichloromethane: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A crystalline solid | | pka | 12.68±0.60(Predicted) |
| | FD 211 Usage And Synthesis |
| Description | FD-211 is a δ lactone originally isolated from M. lutea with anticancer activity.1 It is cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 μg/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 μg/ml). FD-211 also inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 μg/ml for all). | | References | 1. Nozawa, O., Okazaki, T., Sakai, N., et al. A novel bioactive δ lactone FD-211. Taxonomy, isolation and characterization J. Antibiot. (Tokyo) 48(2),113-118(1995). |
| | FD 211 Preparation Products And Raw materials |
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