| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Siramesine
CAS:163630-79-3
Purity:>=98% (HPLC) Package:5mg, 25mg Remarks:SML0976
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| | Lu 28-179 Basic information |
| Product Name: | Lu 28-179 | | Synonyms: | Siramesine fumarate salt;Lu 28-179;1′-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4′-piperidine] fumarate salt;Siramesine (fumarate);Siramesine fumarate salt >=98% (HPLC) | | CAS: | 163630-79-3 | | MF: | C34H35FN2O5 | | MW: | 570.66 | | EINECS: | | | Product Categories: | | | Mol File: | 163630-79-3.mol |  |
| | Lu 28-179 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble20mg/mL, clear | | form | powder | | color | white to beige |
| | Lu 28-179 Usage And Synthesis |
| Biochem/physiol Actions | Siramesine is a blood-brain barrier penetrant, selective and potent sigma-2 receptor agonist, which exhibits potent and very long-lasting anxiolytic effects in rodents. Also, siramesine is a lysosome-destabilizing agent that causes lysosomal cell death in varies immortalized and cancer cell lines. |
| | Lu 28-179 Preparation Products And Raw materials |
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