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| 融点 | 52-54°C | | 比旋光度 | -13.5 º (c=2.5, 1.5N NaOH) | | 沸点 | 125 °C | | 比重(密度) | 1.206 g/mL at 25 °C | | 蒸気圧 | 0.038Pa at 25℃ | | 屈折率 | n20/D 1.427 | | FEMA | 2611 | LACTIC ACID | | 闪点 | >230 °F | | 貯蔵温度 | 2-8°C | | 溶解性 | H2O: 10 mg/mL, clear, colorless | | 酸解離定数(Pka) | pK at 25°, 3.79 | | 外見 | Powder/Solid | | 色 | White | | 臭い (Odor) | odorless acidic | | PH | 2.8 (20°C, 10g/L in H2O) | | においのタイプ | odorless | | 光学活性 (optical activity) | [α]20/D 13.5°, c = 2.5 in 1.5 M NaOH | | 水溶解度 | SOLUBLE | | Sensitive | Hygroscopic | | JECFA Number | 930 | | Merck | 14,5337 | | BRN | 1720251 | | InChIKey | JVTAAEKCZFNVCJ-REOHCLBHSA-N | | LogP | -0.54 at 20℃ | | CAS データベース | 79-33-4(CAS DataBase Reference) | | NISTの化学物質情報 | (s)-2-Hydroxypropanoic acid(79-33-4) | | EPAの化学物質情報 | L-Lactic acid (79-33-4) |
| 外観 | 無色～わずかにうすい黄色, 澄明の液体 | | 定義 | 本品は、次の化学式で表される有機酸である。 | | 溶解性 | 水, エタノール, アセトンに易溶。水、エタノール及びジエチルエーテルに極めて溶けやすく、クロロホルム、石油ベンジン及び二硫化炭素にほとんど溶けない。 | | 解説 | L-乳酸は解糖の最終産物としてピルビン酸の還元によって生ずるが、乳酸デヒドロゲナーゼがこの反応を触媒する。柱状晶。融点53℃。比旋光度（＋）2.6度で、吸湿性。休息時にも血液中に正常成分として少量存在するが、運動時には筋肉中のグリコーゲンから大量に生じ、血液中の濃度が増加する。 | | 用途 | 有機合成原料。医薬原料。 | | 用途 | 醸造工業?有機合成原料,食品添加物(飲料用他),乳酸塩?医薬原料 (NITE CHRIP) | | 化粧品の成分用途 | pH調整剤、保湿.湿潤剤、保水剤、剥離剤、皮膚コンディショニング剤、香料 | | 化学的特性 | Crystalline Solid | | 使用 | Lactic acid has been used:
- as a component in substrate solution II for lactate dehydrogenase reaction
- as an additive in storage solution A
- as a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses
| | 使用 | Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o | | 使用 | It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burn injury. It is used in the agricultural, chemical, leather processing, pharmaceuticals, and cosmetics industries, used as an electroplating agent, food/feed additive, pH regulator, cleaning/washing agent, and tanning agent; used to flavor animal feeds; used as a solvent and intermediate in chemical production, as a pH regulator in fabric finishing, and in paints, coatings, soaps, and cleaning products; used to make large scale and fine chemicals, pulp-paper-paper products, food products, and plastic products, in mining, health services, agriculture-forestry-fishing, and building and construction work. | | 定義 | ChEBI: An optically active form of lactic acid having (S)-configuration. | | 一般的な説明 | L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81). | | 燃焼性と爆発性 | Not classified | | Biochem/physiol Actions | L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase. | | 純化方法 | Purify lactic acid by fractional distillation at 0.1mm pressure, followed by fractional crystallisation from diethyl ether/isopropyl ether (1:1, dried with sodium). [Borsook et al. J Biol Chem 102 449 1933.] The solvent mixture, *benzene/diethyl ether (1:1) containing 5% pet ether (b 60-80o) has also been used. [Brin Biochemical Preparations 3 61 1953, Beilstein 3 IV 633.] |
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