- PF 1022A
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- $296.00 / 1mg
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2024-10-24
- CAS:133413-70-4
- Min. Order:
- Purity:
- Supply Ability: 10g
- PF 1022A
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- $1.00 / 1g
-
2019-12-26
- CAS:133413-70-4
- Min. Order: 1g
- Purity: ≥98%
- Supply Ability: g/kg/Ton
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| | PF 1022A Basic information |
| Product Name: | PF 1022A | | Synonyms: | PF 1022A;Cyclo(D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl);PF1022A; PF-1022A;Cyclo[(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl];(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-Dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octaone;(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone | | CAS: | 133413-70-4 | | MF: | C52H76N4O12 | | MW: | 949.2 | | EINECS: | | | Product Categories: | | | Mol File: | 133413-70-4.mol |  |
| | PF 1022A Chemical Properties |
| Melting point | 89-92 °C | | Boiling point | 1086.6±65.0 °C(Predicted) | | density | 1.070±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at -20°C | | solubility | DMSO: 43 mg/ml | | form | A crystalline solid | | pka | -1.09±0.70(Predicted) | | color | White to off-white |
| | PF 1022A Usage And Synthesis |
| Uses | PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3]. | | Definition | ChEBI: PF1022A is a cyclooctadepsipeptide. | | References | [1] Dornetshuber R, et al. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44. DOI:10.1016/j.bcp.2009.01.005
[2] Sasaki T, et al. A new anthelmintic cyclodepsipeptide, PF1022A. J Antibiot (Tokyo). 1992 May;45(5):692-7. DOI:10.7164/antibiotics.45.692
[3] Nwosu U, et al. Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology. 2011 Aug;138(9):1193-201. DOI:10.1017/S003118201100076X |
| | PF 1022A Preparation Products And Raw materials |
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