(R)-4-[1-羟基-2-[[4-(4-羟基苯基)丁基]氨基]乙基]-1,2-苯二醇
中文名称 | (R)-4-[1-羟基-2-[[4-(4-羟基苯基)丁基]氨基]乙基]-1,2-苯二醇 |
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中文同义词 | (R)-4-[1-羟基-2-[[4-(4-羟基苯基)丁基]氨基]乙基]-1,2-苯二醇;化合物 T10364 |
英文名称 | 4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol |
英文同义词 | ARBUTAMINE (Hydrochloride);4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;Arbutamina;Arbutamina [inn-spanish];Arbutamine [inn:ban];Arbutaminum;Arbutaminum [inn-latin];Unii-B07L15yaev |
CAS号 | 128470-16-6 |
分子式 | C18H23NO4 |
分子量 | 317.38 |
EINECS号 | |
相关类别 | Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals |
Mol文件 | 128470-16-6.mol |
结构式 | ![]() |
(R)-4-[1-羟基-2-[[4-(4-羟基苯基)丁基]氨基]乙基]-1,2-苯二醇 性质
沸点 | 578.3±50.0 °C(Predicted) |
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密度 | 1.262±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C, protect from light, stored under nitrogen |
酸度系数(pKa) | 9.60±0.10(Predicted) |
形态 | 固体 |
颜色 | 黄至棕色 |
Arbutamine 是一种短效的,非选择性 β-肾上腺素受体 (β-adrenoceptor) 激动剂,可增加心率,心脏收缩力和收缩压。Arbutamine 是一种用于儿科心脏应激因子的儿茶酚胺。
β-adrenoceptor
Arbutamine (i.v.; 5, 10, 50, 100, and 250 ng/kg/min) increases mean heart rate, peak positive left ventricular pressure and its first time-derivative, and normal-zone myocardial thickening in 8 open-chest dogs (mean weight, 26.91 kg).