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| FMOC-5-AMINOPENTANOIC ACID Basic information |
Product Name: | FMOC-5-AMINOPENTANOIC ACID | Synonyms: | FMOC-5-AMINOPENTANOIC ACID;FMOC-NH-(CH2)4-COOH;FMOC-APE(5)-OH;RARECHEM EM WB 0074;N-(9-FLUORENYLMETHYLOXYCARBONYL)-5-AMINO-PENTANOIC ACID;5-(FMOC-AMINO)PENTANOIC ACID;5-(9-FLUORENYLMETHYLOXYCARBONYL)AMINO-VALERIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-5-AMINOPENTANOIC ACID | CAS: | 123622-48-0 | MF: | C20H21NO4 | MW: | 339.39 | EINECS: | | Product Categories: | Amino Acids | Mol File: | 123622-48-0.mol | |
| FMOC-5-AMINOPENTANOIC ACID Chemical Properties |
Melting point | 135-136 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3)) | Boiling point | 575.8±33.0 °C(Predicted) | density | 1.232±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | pka | 4.71±0.10(Predicted) | form | Powder | color | White | BRN | 3565625 | CAS DataBase Reference | 123622-48-0 |
Safety Statements | 24/25 | WGK Germany | 3 | HazardClass | IRRITANT | HS Code | 29242990 |
| FMOC-5-AMINOPENTANOIC ACID Usage And Synthesis |
Description | Fmoc-5-aminopentanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | Chemical Properties | White powder | Uses | Fmoc-5-aminopentanoic acid, tech grade | Uses | 5-(Fmoc-amino)valeric acid is used as pharmaceutical intermediate. |
| FMOC-5-AMINOPENTANOIC ACID Preparation Products And Raw materials |
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