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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Suppliers list
Company Name: CONIER CHEM AND PHARMA LIMITED
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Products Intro: Product Name:1-(3-(4-bromo-1-methyl-1h-pyrazol-5-yl)-4-methoxyphenyl)-3-(2,4-difluorophenyl)urea
CAS:839713-36-9
Purity:0.99 Package:1kg
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Products Intro: Product Name:1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
CAS:839713-36-9
Purity:95.0%-99.0% Package:1ASSAYS;6.05USD
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Products Intro: Product Name:Nelotanserin；APD125
CAS:839713-36-9
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: CAS:839713-36-9
Purity:0.99 Package:5KG;1KG
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Products Intro: CAS:839713-36-9
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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Basic information
Product Name:1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Synonyms:1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;Urea, N-[3-(4-broMo-1-Methyl-1H-pyrazol-5-yl)-4-Methoxyphenyl]-N'-(2,4-difluorophenyl)-;Nelotanserin;1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;APD125(Nelotanserin);APD 125;APD125;APD-125
CAS:839713-36-9
MF:C18H15BrF2N4O2
MW:437.24
EINECS:
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Mol File:839713-36-9.mol
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Structure
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Chemical Properties
Boiling point 425.9±45.0 °C(Predicted)
density 1.55±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:32.0(Max Conc. mg/mL);73.2(Max Conc. mM)
form Solid
pka12.29±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Usage And Synthesis
UsesNelotanserin is a potent selective 5-HT2A inverse agonist, nelotanserin has low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.
DefinitionChEBI: Nelotanserin is a member of pyrazoles and a ring assembly.
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Preparation Products And Raw materials
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