LY-2608204 manufacturers
- LY-2608204
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- $1.00 / 1g
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2019-12-24
- CAS:1234703-40-2
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 20kg
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| | LY-2608204 Basic information |
| Product Name: | LY-2608204 | | Synonyms: | LY-2608204;(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide;(1R,2S)-2-cyclohexyl-1-(4-(cyclopropylsulfonyl)phenyl)-N-(5-((2-(pyrrolidin-1-yl)ethyl)thio)thiazol-2-yl)cyclopropanecarboxaMide;(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide LY 2608204;CS-898;LY-2608204; LY 2608204;Cyclopropanecarboxamide, 2-cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]-, (1R,2S)-;LY-2608024 | | CAS: | 1234703-40-2 | | MF: | C28H37N3O3S3 | | MW: | 559.81 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1234703-40-2.mol |  |
| | LY-2608204 Chemical Properties |
| density | 1.35 | | storage temp. | Store at -20°C | | solubility | ≥28.35 mg/mL in DMSO; insoluble in H2O; ≥26.2 mg/mL in EtOH | | form | solid | | pka | 8.17±0.70(Predicted) | | color | White to off-white |
| | LY-2608204 Usage And Synthesis |
| Description | LY2608204 is an activator of glucokinase (GK; EC50 = 42 nM). It stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM). LY2608204 (30 mg/kg) decreases plasma glucose levels in a dose-dependent manner in fasted rats. | | target | GK | | references | [1] kj filipski, bd stevens . glucokinase activators in development .2012 books |
| | LY-2608204 Preparation Products And Raw materials |
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