Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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Tel: |
021-65675885 18964387627 |
Email: |
info@efebio.com |
Products Intro: |
Product Name:Oleic Acid-2,6-diisopropylanilide CAS:140112-65-8 Purity:98% Package:5mg;10mg;50mg
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Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:Oleic Acid-2,6-diisopropylanilide CAS:140112-65-8 Purity:>98% Package:1mg;10mg;50mg;100mg;
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Company Name: |
MedBioPharmaceutical Technology Inc
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Tel: |
021-69568360 18916172912 |
Email: |
order@med-bio.cn |
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Product Name:Oleic Acid-2,6-diisopropylanilide CAS:140112-65-8 Purity:98% Package:10mg (solution); 50mg (solution); 5mg (solution) Remarks:Medbio
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:Oleic Acid-2,6-diisopropylanilide CAS:140112-65-8 Package:50mg/RMB 4620;10mg/RMB 1120;5mg/RMB 595
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Oleic Acid-2,6-diisopropylanilide manufacturers
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| Oleic Acid-2,6-diisopropylanilide Basic information |
| Oleic Acid-2,6-diisopropylanilide Chemical Properties |
Boiling point | 557.7±49.0 °C(Predicted) | density | 0.919±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml | pka | 14.98±0.70(Predicted) |
| Oleic Acid-2,6-diisopropylanilide Usage And Synthesis |
Description | AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%. | References | 1. Suckling, K.E., and Stange, E.F. Role of acyl-CoA: Cholesterol acyltransferase in cellular cholesterol metabolism J. Lipid Res. 26(6),647-671(1985). 2. Roth, B.D., Blankley, C.J., Hoefle, M.L., et al. Inhibitors of acyl-CoA: Cholesterol acyltransferase. 1. Identification and structure-activity relationship of a novel series of fatty acid anilide hypocholesterolemic agents J. Med. Chem. 35(9),1609-1617(1992). |
| Oleic Acid-2,6-diisopropylanilide Preparation Products And Raw materials |
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