| Company Name: |
bioleaper
|
| Tel: |
18601717983 |
| Email: |
guojing@bioleaper.com |
| Products Intro: |
Product Name:MK4827
Purity:5mg Package:5mg
|
| Company Name: |
United States Biological
|
| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:MK-4827
|
|
| | MK-4827 Basic information |
| Product Name: | MK-4827 | | Synonyms: | MK-4827 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![MK-4827 Structure]() |
| | MK-4827 Chemical Properties |
| | MK-4827 Usage And Synthesis |
| Description | MK-4827 (tosylate), also known as Nipaparib, is a kind of small molecule PARP (poly ADP-ribose polymerase, a set of enzymes being related to DNA repair, genomic stability and programmed cell death) inhibitor. It is mainly used for treatment of recurrent epithelial ovarian, fallopian tube and primary peritoneal cancer. Niraparib is the inhibitor of PARP-1 and PARP-2, which is involved in DNA repair. The effect of Niraparib can cause DNA damage, apoptosis and cell death, thus killing the tumor cell lines. | | References | https://en.wikipedia.org/wiki/Niraparib
https://en.wikipedia.org/wiki/Poly_(ADP-ribose)_polymerase
https://www.drugbank.ca/drugs/DB11793 |
| | MK-4827 Preparation Products And Raw materials |
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