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| | N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Basic information |
| Product Name: | N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide | | Synonyms: | N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide;LSN2463359;N-(1-Methylethyl)-5-(pridin-4-ylethynyl)pyridine-2-carboxamide;N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide;100859;2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]- | | CAS: | 1401031-52-4 | | MF: | C16H15N3O | | MW: | 265.31 | | EINECS: | 802-759-0 | | Product Categories: | | | Mol File: | 1401031-52-4.mol |  |
| | N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear | | form | powder | | color | white to light brown |
| Hazard Codes | Xi | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| | N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Usage And Synthesis |
| Uses | LSN 2463359 is used as a positive and potent allosteric modulator of the mGlu5 receptor (1,2). LSN 2463359 is highly selective for mGlu5 and exhibits little to no activity for mGlu1-4, mGlu8 and GABAB receptors. Studies showed that LSN 2463359 promotes wakefulness in vivo and cognitive activity. LSN 2463359 also Improve memory and learning characteristics in mice. | | storage | Store at +4°C |
| | N-isopropyl-5-(pyridin-4-ylethynyl)picolinaMide Preparation Products And Raw materials |
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