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| Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Basic information |
| Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Chemical Properties |
Boiling point | 583℃ | density | 1.198 | Fp | 306℃ | solubility | Acetone, Dichloromethane, Methanol | form | Solid | pka | 11.60±0.70(Predicted) | color | Foamy |
| Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Usage And Synthesis |
Uses | N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. |
| Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Preparation Products And Raw materials |
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