| Company Name: |
Shaanxi Istare Biotechnology Co., Ltd.
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| Tel: |
18682931470 |
| Email: |
2142355700@qq.com |
| Products Intro: |
Product Name:3,4-dichloro-N-[(1R)-1-[4-ethyl-5-[3-(4-methyl-1-piperazinyl)phenoxy]-4H-1,2,4-triazol-3-yl]ethyl]-benzenesulfonamide
CAS:945725-50-8
Purity:98% Package:100 mg, 250 mg, 1g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:TASP 0277308
CAS:945725-50-8
Package:5mg/RMB 5670
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| | TASP 0277308 Basic information |
| Product Name: | TASP 0277308 | | Synonyms: | TASP 0277308;3,4-dichloro-N-[(1R)-1-[4-ethyl-5-[3-(4-methylpiperazin-1-yl)phenoxy]-1,2,4-triazol-3-yl]ethyl]benzenesulfonamide;3,4-dichloro-N-[(1R)-1-{4-ethyl-5-[3-(4-methylpiperazin-1-yl)phenoxy]-4H-1,2,4-triazol-3-yl}ethyl]benzenesulfonamide;Benzenesulfonamide, 3,4-dichloro-N-[(1R)-1-[4-ethyl-5-[3-(4-methyl-1-piperazinyl)phenoxy]-4H-1,2,4-triazol-3-yl]ethyl]-;3,4-dichloro-N-[(1R)-1-[4-ethyl-5-[3-(4-methyl-1-piperazinyl)phenoxy]-4H-1,2,4-triazol-3-yl]ethyl]-benzenesulfonamide | | CAS: | 945725-50-8 | | MF: | C23H28Cl2N6O3S | | MW: | 539.48 | | EINECS: | | | Product Categories: | | | Mol File: | 945725-50-8.mol |  |
| | TASP 0277308 Chemical Properties |
| Boiling point | 707.5±70.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | solubility | Soluble to 5 mM in DMSO | | pka | 7.90±0.50(Predicted) |
| | TASP 0277308 Usage And Synthesis |
| Description | TASP0277308 is a potent and selective sphingosine 1-phosphate 1 (S1P1) receptor antagonist (IC50 = 7.8 nM). TASP0277308 inhibited S1P- as well as VEGF-induced cellular responses, including migration and proliferation of human umbilical vein endothelial cells. Furthermore, TASP0277308 effectively blocked a VEGF-induced tube formation in vitro and significantly suppressed tumor cell-induced angiogenesis in vivo. | | storage | Store at -20°C |
| | TASP 0277308 Preparation Products And Raw materials |
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