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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
Products Intro: |
Product Name:6-[[3-[(1S)-2-Methoxy-1-Methylethoxy]-5-[(1S)-1-Methyl-2-phenylethoxy]benzoyl]aMino]-3-pyridinecarboxylic Acid CAS:851884-87-2 Package:100Mg,25Mg,50Mg
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Company Name: |
AdooQ BioScience, LLC
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Tel: |
+1 (866) 930-6790 |
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info@adooq.com |
Products Intro: |
Product Name:GKA50 CAS:851884-87-2 Purity:98% Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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Product Name: | GKA-50 | Synonyms: | GKA 50;GKA50;GKA-50;6-[[3-[(1S)-2-Methoxy-1-Methylethoxy]-5-[(1S)-1-Methyl-2-phenylethoxy]benzoyl]aMino]-3-pyridinecarboxylic Acid;OCBMECSFDVUYQN-ROUUACIJSA-N;GKA-50; GKA 50;3-Pyridinecarboxylic acid, 6-[[3-[(1S)-2-methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino]- | CAS: | 851884-87-2 | MF: | C26H28N2O6 | MW: | 464.51 | EINECS: | | Product Categories: | | Mol File: | 851884-87-2.mol | ![GKA-50 Structure](CAS/20150408/GIF/851884-87-2.gif) |
| GKA-50 Chemical Properties |
Boiling point | 607.0±55.0 °C(Predicted) | density | 1.247±0.06 g/cm3(Predicted) | storage temp. | -20°C | solubility | DMSO: soluble15mg/mL, clear | form | powder | pka | 3.49±0.10(Predicted) | color | white to beige |
Hazard Codes | Xn | Risk Statements | 22 | WGK Germany | 3 |
| GKA-50 Usage And Synthesis |
Uses | 6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino]-3-pyridinecarboxylic Acid, is one of the glucokinase activator derivatives. GKAs activate GK via binding to an allosteric site of the enzyme. They increase glucose-stimulated insulin secretion and decrease blood glucose levels. Also, glucokinase activator GKA50 is shown to be able to promote proliferation by increasing the cell volume and thus, preventing apoptosis in rat pancreatic insulinoma-1 beta cell. | storage | Store at -20°C |
| GKA-50 Preparation Products And Raw materials |
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