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| | CID 16020046 Basic information | | Uses |
| Product Name: | CID 16020046 | | Synonyms: | 4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid;CID 16020046;4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid;CID16020046 (CID 16020046);Benzoic acid, 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-;CS-1189;CID16020046;CID 16020046;CID 16020046;C390-0219 | | CAS: | 834903-43-4 | | MF: | C25H19N3O4 | | MW: | 425.44 | | EINECS: | | | Product Categories: | | | Mol File: | 834903-43-4.mol |  |
| | CID 16020046 Chemical Properties |
| Boiling point | 748.1±60.0 °C(Predicted) | | density | 1.425±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble1mg/mL, clear (warmed) | | pka | 4.27±0.10(Predicted) | | form | powder | | color | white to beige |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| | CID 16020046 Usage And Synthesis |
| Uses | CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization. | | Uses | CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization. | | Biochem/physiol Actions | CID16020046 is a potent and a selective GPR55 antagonist that inhibits GPR55-mediated ERK1/2 phosphorylation. CID16020046 inhibits LPI-induced Ca2+ signaling in HEK-GPR55 cells. | | storage | Store at +4°C |
| | CID 16020046 Preparation Products And Raw materials |
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