| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:LM11A-31 dihydrochloride
CAS:1214672-15-7
Purity:>=95% (HPLC) Package:25MG Remarks:SML0664-25MG
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| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:(Rac)-LM11A-31 dihydrochloride
CAS:1214672-15-7
Purity:98% HPLC Package:100mg，250mg，1g
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| | 2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-pentanamide dihydrochloride Basic information |
| | 2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-pentanamide dihydrochloride Chemical Properties |
| storage temp. | 2-8°C | | solubility | Water: ≥ 200 mg/mL (632.37 mM); Ethanol: 100 mg/mL (316.19 mM) | | form | oil | | color | colorless to yellow |
| | 2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-pentanamide dihydrochloride Usage And Synthesis |
| Uses | LM11A-31 dihydrochloride has been used to study the effect of p75 neurotrophin receptor (p75 NTR) blockade, by non-peptide LM11A-31 ligand, on PC12?cell viability. | | Biochem/physiol Actions | LM11A-31 is a non-peptide ligand of the p75 neurotrophin receptor (p75NTR). LM11A-31 blocks pro-NGF induced cell death in neuronal cultures, and protects neuronal cells from the the cytotoxic effects of cisplatin or methotrexate. Oral administration of LM11A-31 promotes the survival of oligodendrocytes and myelinated axons in a mouse spinal cord injury model and improves function in both weight-bearing and non-weight bearing tests. |
| | 2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-pentanamide dihydrochloride Preparation Products And Raw materials |
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