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Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
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Product Name:PDI inhibitor 16F16
CAS:922507-80-0
Purity:>=98% (HPLC) Package:5mg, 25mg Remarks:SML0021
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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sales@dcchemicals.com |
| Products Intro: |
Product Name:PDI inhibitor 16F16
CAS:922507-80-0
Purity:98% HPLC Package:100mg，250mg，1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
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Product Name:16F16
CAS:922507-80-0
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Energy Chemical
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021-58432009 400-005-6266 |
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marketing@energy-chemical.com |
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Product Name:PDI inhibitor 16F16 >=98% (HPLC)
CAS:922507-80-0
Purity:NULL Package:25mg;5mg Remarks:NULL
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| Company Name: |
JiangSu Star Science Co.,Ltd
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400-605-7200 17312445705 |
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sales022@b2star.com |
| Products Intro: |
Product Name:PDI inhibitor 16F16
CAS:922507-80-0
Package:10g; 100g;500g;1kg;5KG;10KG
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| | Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate Basic information |
| Product Name: | Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate | | Synonyms: | Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate;PDI inhibitor 16F16;2-(2-Chloroacetyl)-2,3,4,9-tetrahydro-1-methyl-1H-pyrido[3,4-b]indole-1-carboxylic acid methyl ester;1H-Pyrido[3,4-b]indole-1-carboxylic acid, 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-methyl-, methyl ester;PDI inhibitor 16F16 >=98% (HPLC);16F16,16F-16 | | CAS: | 922507-80-0 | | MF: | C16H17ClN2O3 | | MW: | 320.77 | | EINECS: | | | Product Categories: | | | Mol File: | 922507-80-0.mol | ![Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate Structure](CAS/20180629/GIF/922507-80-0.gif) |
| | Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble12mg/mL, clear | | form | powder | | color | white to tan |
| | Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate Usage And Synthesis |
| Uses | PDI inhibitor 16F16 may be used in protein disulfide isomerase-mediated cell signaling studies. | | Biochem/physiol Actions | 16F16 is a protein disulfide isomerase (PDI) inhibitor, first identified in a screen for compounds that prevent apoptosis induced by mutant huntingtin protein. 16F16 not only suppressed apoptosis induced by the misfolded protein mutant hungtingtin, it also protected rat neurons from cell death triggered by Aβ peptide. The actions of this inhibitor helped to identify a new mechanism in which a cell death pathway is regulated by protein misfolding via PDI upregulation. |
| | Methyl 2-(2-chloroacetyl)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate Preparation Products And Raw materials |
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