| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Anti-HSPA2 antibody produced in rabbit
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Purity:purified immunoglobulin, buffered aqueous solution Remarks:clone 3A11-1A2, purified immunoglobulin, buffered aqueous solution
|
|
| | Anti-Heat shock-related 70 kDa protein 2 antibody produced in rabbit Basic information |
| | Anti-Heat shock-related 70 kDa protein 2 antibody produced in rabbit Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution | | biological source | rabbit |
| | Anti-Heat shock-related 70 kDa protein 2 antibody produced in rabbit Usage And Synthesis |
| Uses | Anti-HSPA2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | Heat shock-related 70kDa protein 2 (HSPA2) is encoded by the HSPA2 gene localized in the human chromosome 14q23.3. It is one of the isoforms of HSP-70 and is a cytosolic family member that undergoes methylation. HspA2 shows 85% homology to HspA1L isoform. | | Biochem/physiol Actions | Heat shock-related 70kDa protein 2 is a testis-specific member of the HSP70 family and is correlated with sperm maturity, function and fertility. The protein is important for cancer cell growth and metastasis. It is identified as a potential cancer-promoting protein expressed at abnormal levels in a subset of cancers. HSPA2 has an important role in esophageal squamous cell carcinoma (ESCC) and overexpression of this gene may contribute to the malignant progression of ESCC. Its expression significantly correlates with sperm concentration and morphology. HSPA2 may play an important role in capacitation and fertilisation processes. |
| | Anti-Heat shock-related 70 kDa protein 2 antibody produced in rabbit Preparation Products And Raw materials |
|