| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Human TGF-β 1 ELISA Kit
Purity:for serum, plasma, and cell culture supernatants Package:1kit Remarks:RAB0460
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| | Human TGF-β 1 ELISA Kit Basic information |
| | Human TGF-β 1 ELISA Kit Chemical Properties |
| | Human TGF-β 1 ELISA Kit Usage And Synthesis |
| Uses | For research use only. Not for use in diagnostic procedures.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells. | | General Description | The Human TGF-β 1 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-β 1 in serum, plasma, cell culture supernatants and urine. | | Biochem/physiol Actions | Transforming growth factor-β1 (TGF-β1) is a pluripotential cytokine that plays a vital role in the homeostasis of peripheral CD4+CD25+ regulatory T cells and regulation of FOXP3 (forkhead box P3) expression in vivo. Binding of TGF-β1 to its receptor, activates members of the SMAD protein family involved in gene regulation. Study shows that reduced expression of circulating transforming growth factor-β1 (TGF-β1) might contribute to systemic lupus erythematosus (SLE) development. Polymorphism of TGF-β1 is associated with pathogenesis of rheumatoid arthritis (RA) and pneumoconiosis. Serum TGF-β1 expression is elevated in systemic sclerosis (SSc) patients. Serum TGF-β1 functions as a potential biomarker of Guillain-Barré syndrome (GBS) and SSc. |
| | Human TGF-β 1 ELISA Kit Preparation Products And Raw materials |
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