Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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Tel: |
027-65317797 15926423062 |
Email: |
422450190@qq.com |
Products Intro: |
Product Name:Recombinant Human NDRG1 Protein, His Tag Purity:90% as determined by SDS-PAGE Package:50ug;100ug
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| wu:fb60h02 Basic information |
Product Name: | wu:fb60h02 | Synonyms: | Anti-ndrg1 antibody produced in rabbit;cb775;MGC63944;ndrg1;wu:fb60h02;Recombinant Human NDRG1 Protein, His Tag | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| wu:fb60h02 Chemical Properties |
storage temp. | -20°C | form | buffered aqueous glycerol solution |
| wu:fb60h02 Usage And Synthesis |
Uses | Anti-NDRG1 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | Biochem/physiol Actions | NDRG1 (N-myc downstream regulated 1) is a Rab4a (Ras-related protein Rab-4A) effector protein associated with cell proliferation, differentiation, and invasion. It localizes at the perinuclear recycling/sorting vesicles of Trans Golgi network. It is essentially required for the p53-dependent apoptosis. At the site of DNA damage, its elevated expression identifies the target genes required for mediating apoptosis. It also plays a major role in the recycling and stabilization of adhesion molecule E-cadherin. In endosome recycling, NDRG1 interacts with the membrane bound Rab4aGTPase. Reports show that NDRG1 acts as a biomarker in the development of Colorectal cancer (CRC). |
| wu:fb60h02 Preparation Products And Raw materials |
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