| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Ceramide Kinase FLAG tag active human
Purity:>=40% (SDS-PAGE) Package:10μg Remarks:SRP0339
|
|
| Product Name: | hCERK | | Synonyms: | Ceramide Kinase FLAG tag active human;CERK;hCERK;LK4;DKFZp434E0211;FLJ21430;FLJ23239;Acylsphingosine kinase | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![hCERK Structure]() |
| | hCERK Chemical Properties |
| storage temp. | -70°C | | form | aqueous solution |
| | hCERK Usage And Synthesis |
| Uses | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. | | General Description | Human ceramide kinase (CERK) (GenBank Accession No. NM_022766), 1-537 (end) with C-terminal Flag-tag, MW= 60 kDa, expressed in Baculovirus expression system. | | Biochem/physiol Actions | Ceramide kinase (CERK) is an enzyme involved in sphingolipid metabolism and in the synthesis of ceramide-1-phosphate. It associates with calmodulin and at the time of Fc receptor-mediated phagocytosis, it aggregates in lipid rafts. CERK may have a role in calcium signaling. The protein functions in the phagocytosis of polymorphonuclear leukocytes and degranulation of mast cells. |
| | hCERK Preparation Products And Raw materials |
|