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| | Ribocil Basic information |
| Product Name: | Ribocil | | Synonyms: | Ribocil;4(3H)-Pyrimidinone, 2-[1-[[2-(methylamino)-5-pyrimidinyl]methyl]-3-piperidinyl]-6-(2-thienyl)-;Inhibitor,Ribocil,Bacterial,inhibit;2-(1-((2-(methylamino)pyrimidin-5-yl)methyl)piperidin-3-yl)-6-(thiophen-2-yl)pyrimidin-4(1H)-one | | CAS: | 1381289-58-2 | | MF: | C19H22N6OS | | MW: | 382.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1381289-58-2.mol |  |
| | Ribocil Chemical Properties |
| Boiling point | 587.8±60.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:10.0(Max Conc. mg/mL);2.61(Max Conc. mM) | | form | A crystalline solid | | pka | 8.44±0.50(Predicted) | | color | White to off-white |
| | Ribocil Usage And Synthesis |
| Description | Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN; ) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB, a gene responsible for the synthesis and transport of riboflavin. Ribocil depletes cellular levels of riboflavin with an IC50 value of 0.3 μM and inhibits E. coli growth with an MIC value of 2 μg/ml. |
| | Ribocil Preparation Products And Raw materials |
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