Company Name: |
Apollo Scientific Ltd.
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Tel: |
44 161 406 0505 |
Email: |
sales@apolloscientific.co.uk |
Products Intro: |
Product Name:Mouse Anti Human Interferon-gamma
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| ANTI-HUMAN IFN-GAMMA Basic information |
Product Name: | ANTI-HUMAN IFN-GAMMA | Synonyms: | ANTI-HUMAN IFN-G, CLONE B-B1;ANTI-HUMAN IFN-G, CLONE B-B1, MONOCLONAL ANTIBODY;ANTI-HUMAN IFN-G, CLONE F12;ANTI-HUMAN IFN-G, CLONE F12, MONOCLONAL ANTIBODY;ANTI-HUMAN IFN-G, CLONE F14;ANTI-HUMAN IFN-G, CLONE F14, MONOCLONAL ANTIBODY;ANTI-HUMAN IFN-G POLYCLONAL ANTIBODY;ANTI-HUMAN IFN-G | CAS: | | MF: | | MW: | 0 | EINECS: | 202-739-6 | Product Categories: | | Mol File: | Mol File | |
| ANTI-HUMAN IFN-GAMMA Chemical Properties |
storage temp. | -20°C | form | lyophilized powder |
Hazard Codes | Xn | Risk Statements | 22 | Safety Statements | 22-24/25 | WGK Germany | 3 |
| ANTI-HUMAN IFN-GAMMA Usage And Synthesis |
Uses | The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 2-4 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. | Uses | Anti-interferon-γ antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. For immunohistochemistry the recommended concentration is 5-15 μg/ml. The antibody has been used for immunohistochemistry of human cervical spinal cord sections using a concentration of 15 μg/ml. The antibody is suitable for neutralization reactions. | General Description | IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis. The most studied function of IFN-γ is priming the antigen presenting cells by upregulating major histocompatibility (MHC) Class I molecules. IFN-γ has clinical applications in autoimmune diseases (rheumatoid arthritis), multiple sclerosis, cancer, HIV and fungal infections Anti-Interferon-γ recognizes human Interferon-γ. | Biochem/physiol Actions | Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis. |
| ANTI-HUMAN IFN-GAMMA Preparation Products And Raw materials |
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