SYP-5

SYP-5 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:1384268-04-5
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:SYP-5
CAS:1384268-04-5
Purity:98.31% Package:1mg;30USD|5mg;61USD|10mg;101USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:SYP-5
CAS:1384268-04-5
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Nanjing Doge Biomedical Technology Co., Ltd
Tel: +86-25-58227606 +86-15305155328
Email: sales@dogechemical.com
Products Intro: Product Name:SYP-5
CAS:1384268-04-5
Package:5g;100g;1KG;25KG
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:SYP-5
CAS:1384268-04-5
Purity:98.31% Package:1mg;30USD|5mg;61USD|10mg;101USD

SYP-5 manufacturers

  • SYP-5
  • SYP-5 pictures
  • $30.00 / 1mg
  • 2024-11-19
  • CAS:1384268-04-5
  • Min. Order:
  • Purity: 98.31%
  • Supply Ability: 10g
  • SYP-5
  • SYP-5 pictures
  • $30.00 / 1mg
  • 2024-11-19
  • CAS:1384268-04-5
  • Min. Order:
  • Purity: 98.31%
  • Supply Ability: 10g
SYP-5 Basic information
Product Name:SYP-5
Synonyms:SYP-5;SYP5; SYP 5;2-Propen-1-one, 1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(2-thienyl)-, (2E)-;SYP-5 >=98% (HPLC);SYP-5,Inhibitor,HIFs,Hypoxia-inducible factors,SYP5,inhibit,HIF-PH,SYP 5,HIF/HIF Prolyl-Hydroxylase;(E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS:1384268-04-5
MF:C18H16O3S
MW:312.38
EINECS:
Product Categories:
Mol File:1384268-04-5.mol
SYP-5 Structure
SYP-5 Chemical Properties
Boiling point 502.0±50.0 °C(Predicted)
density 1.263±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF:30.0(Max Conc. mg/mL);96.04(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.96(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);80.03(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);3.2(Max Conc. mM)
form A solid
pka7.12±0.40(Predicted)
color Yellow to orange
Safety Information
MSDS Information
SYP-5 Usage And Synthesis
Biological ActivitySYP-5, an inhibitor of Hypoxia-inducible factor-1 (HIF-1), inhibits tumor cell migration and invasion and tumor angiogenesis.
in vitroSYP-5 inhibits hypoxia-induced upregulation of HIF-1. It inhibits HIF-1 and downstream gene expression in Hep3B and Bcap37 cells. It inhibits tumor cell migration and invasion, as well as tumor angiogenesis, which are mediated by suppressing PI3K/AKT- and MAPK/ERK-dependent HIF-1 pathway. The proteins of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMP)-2 that are targets of HIF-1, are down -regulated by SYP-5.
target
TargetValue
HIF-1
()
SYP-5 Preparation Products And Raw materials
Tag:SYP-5(1384268-04-5) Related Product Information