CC-885 manufacturers
- CC-885
-
- $51.00 / 1mg
-
2024-11-19
- CAS:1010100-07-8
- Min. Order:
- Purity: 99.08%
- Supply Ability: 10g
- CC-885
-
- $51.00 / 1mg
-
2024-11-19
- CAS:1010100-07-8
- Min. Order:
- Purity: 99.08%
- Supply Ability: 10g
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| Product Name: | CC-885 | | Synonyms: | CC-885;Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-;1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea;Ligands for E3 Ligase,CC-885,CC 885,E3 ligase-recruiting Moiety,CC885,Inhibitor,inhibit | | CAS: | 1010100-07-8 | | MF: | C22H21ClN4O4 | | MW: | 440.88 | | EINECS: | | | Product Categories: | | | Mol File: | 1010100-07-8.mol |  |
| | CC-885 Chemical Properties |
| solubility | DMSO:40.0(Max Conc. mg/mL);90.72(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.45(Max Conc. mM)
DMF:12.5(Max Conc. mg/mL);28.35(Max Conc. mM) | | form | A crystalline solid | | color | White to off-white |
| | CC-885 Usage And Synthesis |
| Description | CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome. | | target | CC-885 is a cereblon (CRBN) modulator. |
| | CC-885 Preparation Products And Raw materials |
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