BOMETOLOL HYDROCHLORIDE
| 中文名称 | BOMETOLOL HYDROCHLORIDE |
|---|---|
| 中文同义词 | 化合物 T13585;波美洛尔盐酸盐 |
| 英文名称 | Bometolol Hydrochloride |
| 英文同义词 | Bometolol Hydrochloride |
| CAS号 | 65023-16-7 |
| 分子式 | C25H33ClN2O7 |
| 分子量 | 509 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 65023-16-7.mol |
| 结构式 |  |
BOMETOLOL HYDROCHLORIDE 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
Bometolol Hydrochloride 是一种 beta-adrenergic 阻滞剂，可用于高血压等心血管疾病的研究。
Beta-adrenergic receptor
Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats.