[METHYL-D3]METANICOTINE 基本信息
| 中文名称 | [METHYL-D3]METANICOTINE |
|---|---|
| 中文同义词 | |
| 英文名称 | [METHYL-D3]METANICOTINE |
| 英文同义词 | [METHYL-D3]METANICOTINE;[METHYL-D3]RJR2403;(E)-N-[METHYL-D3]-4-(3-PYRIDINYL)-3-BUTEN-1-AMINE;(E)-N-[Methyl-d3]-4-(3-pyridinyl)-3-buten-1-amine, [Methyl-d3]RJR2403;Methyl Metanicotine-d3;(E)-Metanicotine-d3;Rivanicline-d3;(E)-4-pyridin-3-yl-N-(trideuteriomethyl)but-3-en-1-amine |
| CAS号 | 220088-40-4 |
| 分子式 | C10H11D3N2 |
| 分子量 | 165.25 |
| EINECS号 | |
| 相关类别 | Nicotine Derivatives |
| Mol文件 | Mol File |
| 结构式 | ![[METHYL-D3]METANICOTINE 结构式](StructureFile/ChemBookStructure6/GIF/CB1340743.gif) |
[METHYL-D3]METANICOTINE 性质
| 沸点 | 99-101°C/0.4mm Hg |
|---|---|
| 储存条件 | Amber Vial, -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于氯仿、甲醇 |
| 形态 | 油状 |
| 颜色 | 透明无色 |
| 稳定性 | 感光 |
| CAS 数据库 | 220088-40-4 |
用途
An alkaloid found in the leaves of Duboisia Hopwoodii, and a constitutent of tobacco smoke. Also used a potential drug for the treatment of senile dementia of the Alzheimer鈥檚 type and currently being
investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to periphera
l ganglionic and muscle-type nicotinic acetylcholine receptors.