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Product Name: | AB-423 | Synonyms: | AB-423;CS-2686;AB423;AB-423;AB 423;Benzamide, N-(3,4-difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]-;N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide;AB 423,HBV,AB423,inhibit,Hepatitis B virus,AB-423,Inhibitor | CAS: | 1572510-80-5 | MF: | C17H17F3N2O3S | MW: | 386.39 | EINECS: | | Product Categories: | | Mol File: | 1572510-80-5.mol | ![AB-423 Structure](CAS/20200611/GIF/1572510-80-5.gif) |
| AB-423 Chemical Properties |
density | 1.372±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO:88.5(Max Conc. mg/mL);229.04(Max Conc. mM) Ethanol:77.0(Max Conc. mg/mL);199.28(Max Conc. mM) | form | Solid | pka | 10.84±0.70(Predicted) | color | White to off-white | CAS DataBase Reference | 1572510-80-5 |
| AB-423 Usage And Synthesis |
Uses | N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide, is an inhibitor of HBV capsid assembly. AB-423 shows inhibitory effect on rcDNA production in AML12-HBV10 and HepDE19 cells with EC50s of ~0.260 μM |
| AB-423 Preparation Products And Raw materials |
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